Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. BCL6 is a master transcription factor for regulation of T follicular helper cells (T FH cells) proliferation. [5] …

2024年12月24日 · BCL6 (BCL6 Transcription Repressor) is a Protein Coding gene. Diseases associated with BCL6 include Intravascular Large B-Cell Lymphoma and High-Grade B-Cell …

2022年12月2日 · B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the …

B cell lymphoma 6 (BCL6) is a conserved multi-domain protein that functions principally as a transcriptional repressor. This protein regulates many pivotal aspects of immune cell …

2 天之前 · BCL6 is a transcription factor located at 3q27 and is required for germinal center B cells formation and follicular helper T cells (TFH) differentiation

B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the tumor suppressor …

BCL6 is required for GC B-cells to proliferate and tolerate the DNA damage that occurs as a byproduct of this process of immunoglobulin affinity maturation [1].

BCL6 is a transcriptional repressor which has emerged as a critical regulator of germinal centers (GC), the sites where B cells are selected based on the production of antibodies with high …

2022年12月2日 · B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the …

2024年10月11日 · BCL6 is critical for germinal center (GC) formation and the development of high-affinity antibodies, with key roles in the generation and function of GC B cells, follicular …