Murley sustained a foot injury on debut against Ireland in Dublin with Steve Borthwick now contemplating the balance of his backline and back row

England wing Cadan Murley has been ruled out of the Six Nations clash with France at Twickenham on Saturday with a foot problem. If Murley recovers quickly he could be available for fixtures against Italy and Wales later in the Six Nations.

Saracens centre Alex Lozowski replaces the injured Cadan Murley in the England squad for Saturday's Six Nations match with France at Twickenham.

Cadan Murley has emerged as a major doubt for England’s Six Nations meeting with France after suffering a foot injury during his Test debut against Ireland on Saturday.

England will be without Cadan Murley for Saturday's Six Nations match against France at Twickenham. Murley, 25, scored England's opener against Ireland in their 27-22 defeat in Dublin last weekend, but picked up a foot injury in the match,

Cadan Murley will make his international debut against Ireland at the Aviva Stadium on Saturday and admitted he felt a “weird mix of emotions” upon hearing the news. Murley received the tap on the shoulder at breakfast from England ’s head coach Steve Borthwick at breakfast at the start of this week.

Saracens centre Alex Lozowski has been called up to the England squad ahead of Saturday's Six Nations game with France after Cadan Murley, who scored a try on his debut against Ireland, was ruled out with a foot injury,