In line with that, our review highlights the well-accepted mechanisms of action and resistance to the therapy and discusses the progress ... Its activation then triggers a broad spectrum of downstream ...

Collaboration to explore the immunoregulation of NK and T cells within the tumor microenvironment (TME) by CAPTN-3, with the goal of enhancing ...

This article will review the mechanisms of activation of alternative, classical, and lectin pathways, the formation of C3 and C5 convertases, the action of anaphylatoxins ... activation of host immune ...

HCW Biologics (HCWB) announced that it has received clearance of its Investigational New Drug Application, IND, from the U.S. Food and Drug ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

However, activated NK cells can also kill MSCs. MSCs inhibit T-cell proliferation through ... This Review discusses the targets and mechanisms of MSC-mediated immunomodulation and the possible ...

31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T ... cells' in-house DNA repair ...

These studies indicate that Crohn's disease and ulcerative colitis are heterogeneous diseases characterized by various genetic abnormalities that lead to overly aggressive T-cell responses to a ...

In this study, we have unravelled a novel mechanism of TAM-initiated fibrosis and the myofibroblast transition in facilitating PDAC metastasis. The interleukin (IL)-33–ST2–CXCL3–CXCR2 signalling ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

A new imaging technique reveals ribosomes work together when translating mRNA, preventing slowdowns in protein production. This discovery challenges prior beliefs and could revolutionize our ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...