Traditionally, blood sugar regulation has been attributed to the hormones insulin and glucagon, both produced by the pancreas. Insulin lowers blood glucose by promoting its uptake into cells ...

We generated a new type of MHC multimers, which can be monomerized in the presence of a competitor, resulting in rapid loss of the staining reagent. Following dissociation, the T cells are ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

We found IL-8 expression in human islets to be localized to glucagon-positive endocrine cells, suggesting that islet IL-8 is mainly α-cell derived (Fig. 7A, 1-15). Indeed, by electron microscopy ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...

CD4-positive T cells are a subtype of lymphocyte. They are MHC class II-restricted and are important mediators of adaptive immunity. These cells are involved in both the induction and the ...

The best carpet stain removers can be a lifesaver. Many of us have been there, and witnessed that moment when time slows down and a glass of red wine tumbles and splashes across your light carpet.

54 years ago today, The Ramsar Convention on the Sustainable Use of Wetlands was signed in Ramsar, Iran. When stopping to think about it, ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

GCGR Activation Graph GIPR Activation Graph GLP-1R Activation Graph A New Tool for Researchers Developing Dual- and Triple-Agonist Therapies for Obesity, Diabetes, and Other Metabolic Disorders STATE.

And, as it turns out, Tide Free & Gentle is great for pretreating stains too, especially greasy or oily ones. I took this advice, but to make pretreating easier, I put Tide in a spray bottle with ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. While pancreatic beta-cell proliferation has ...