The best multimodal approach for resectable locally advanced esophageal adenocarcinoma is unclear. An important question is whether perioperative chemotherapy is preferable to preoperative ...

The final months of 2024 brought several developments that will have far-reaching implications for global health delivery efforts in the years to come. Closest to home for those of us in the ...

Abelacimab is a fully human monoclonal antibody that binds to the inactive form of factor XI and blocks its activation. The safety of abelacimab as compared with a direct oral anticoagulant in ...

Hunger is an ancestral and evolutionary survival instinct; its importance is evident in the complex and redundant pathways involving all five senses that regulate it. 1,2 Historically, when humans ...

New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...

Social media apps provide patients with a platform to share experiences of medical care that have left them feeling disrespected or judged and can highlight common failures in clinical communication.

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...

Dr. J. Sawalla Guseh II: A 54-year-old male athlete was evaluated in the cardiovascular performance program clinic of this hospital because of progressive exertional dyspnea and chest pain.

Ten years ago, I was in the hospital battling Ebola. My fever rarely relented. I felt so weak that getting up was a herculean task, attempted only a few times a day. Having treated patients with ...

Highly pathogenic avian influenza A(H5N1) viruses are circulating among wild birds and poultry in British Columbia, Canada. 1 These viruses are also recognized to cause illness in humans.

Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate ...

In patients with out-of-hospital cardiac arrest, securing intravenous access for drug delivery is challenging. Whether the intraosseous route can improve clinical outcomes has been uncertain.