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生物谷
6 小时
Clin Cancer Res:新型测试手段或能展现出个体化早期乳腺癌治疗的新前景
这些研究发现支持了RAD51测试在调整早期乳腺癌患者疗法策略上的潜力,未来的生物标志物的驱动研究(比如RADIOLA研究)就旨在验证RAD51在晚期乳腺癌中的作用,其结果预计将会在今年晚些时候公布,而研究人员应该考虑利用目前的数据来完善分层因素并改善 ...
Targeted Oncology
14 小时
FDA Expands PATHWAY HER2 (4B5) Test to Include HER2-Ultralow Status
The PATHWAY HER2 (4B5) test is now FDA-approved to assess HER2-ultralow status in metastatic breast cancer, expanding its ...
Taiwan News
2 小时
Anti-HER2 Bispecific ADC JSKN003 Received Approval to Initiate a Phase III Clinical Study ...
("CSPC") (Stock Code: 1093.HK) jointly announced that anti-HER2 biparatopic antibody-drug conjugate (ADC) JSKN003 has received approval from the Center for Drug Evaluation (CDE) of the National ...
腾讯网
12 天
8 成患者生存超 7 年!ADC 辅助治疗 HER2+ 乳腺癌长期数据来袭
引言恩美曲妥珠单抗(T-DM1)是全球首个获批上市的乳腺癌抗体偶联药物(ADC)。2018 年,发表于 New England Journal of Medicine 的 Ⅲ 期开放标签试验 KATHERINE ...
7 天
on MSN
In HER2+ colorectal cancer, anti-HER2 therapy may be less toxic alternative
Patients whose metastatic colorectal cancer has progressed following chemotherapy and who lack mutations in the RAS and BRAF ...
Targeted Oncology
2 天
T-DXd Reevaluated in HER2-Low/HER2-Negative Breast Cancer After New Trials
During a Case-Based Roundtable event, Laura Huppert, MD, discussed data and considerations around using T-DXd in breast ...
Pharm Exec
1 天
FDA Approves Expanded Label for Roche's Companion Diagnostic to Identify HER2-Ultralow ...
The FDA has approved an expanded label for Roche’s PATHWAY anti-HER2/neu (4B5) Rabbit Monoclonal Primary Antibody test, which ...
腾讯网
10 天
AI赋能乳腺癌风险分层:复旦大学附属肿瘤医院的创新成果
【导读】激素受体阳性(HR+)/人表皮生长因子受体2阴性(HER2-)乳腺癌是最常见的乳腺癌类型,持续复发仍是一个重要的临床问题。目前针对HR+/HER2-乳腺癌患者的复发预测模型仍存在局限性。整合多维数据是预测复发的一种有前途的替代方法。2025年 ...
The American Journal of Managed Care
5 天
FDA Approves First HER2-Ultralow Companion Diagnostic, Expanding Treatment Eligibility
Roche’s PATHWAY HER2 (4B5) test helps identify patients with HER2-ultralow breast cancer, who may be eligible for targeted ...
FierceBiotech
1 天
Roche's Enhertu companion diagnostic secures new FDA approval in HER2-ultralow breast cancer
Roche has secured a new FDA approval for its first companion diagnostic test aimed at identifying breast cancer patients with ...
来自MSN
7 天
FDA expands Enhertu approval to include HER2-ultralow breast cancer patients
Enhertu first secured approval in 2019 for patients with high levels of HER2, a protein that promotes cancer cell growth. In ...
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